1. What are GLP-1 Medications

GLP-1 stands for Glucagon-like peptides, and they are a class of medications that were originally used to help those with type-2 diabetes but are now being used for weight loss.

2. What Makes Retatrutide a Triple G Weight Loss Drug

“The three hormones that the retatrutide molecule simultaneously mimics are glucagon-like peptide-1 (GLP-1), such as agents in the class of GLP-1 agonists that includes liraglutide (Victoza/Saxenda) and semaglutide (Ozempic/Wegovy); the glucose-dependent insulinotropic polypeptide (GIP), the receptor that is also activated by tirzepatide (Mounjaro), a dual-incretin receptor agonist that mimics both GLP-1 and GIP; and glucagon. Survodutide is a dual GLP-1 and glucagon receptor agonist in phase 2 development.” https://www.medscape.com/viewarticle/995316#?form=fpf

3. What Are the Side Effects of GLP-1 Medications

All GLP-1 medications have numerous side effects including nausea, vomiting, and diarrhea. The most recent medication, Retatrutide, has been shown to cause gastroparesis and cyclical vomiting. Additionally, many people experience significant muscle loss which can have substantial long-term effects on metabolism.