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3415: The New Science of Becoming Resilient to Stress

  • June 12, 2025

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TT: The New Science of Becoming Resilient to Stress

We all face stress—but how we respond to it makes all the difference.

Stress can build us up, strengthening our body and immune system… or it can break us down, leading to anxiety, muscle loss, weakened immunity, and faster aging.

The good news? Our body comes equipped with a natural defense system against stress—and when we support it properly, we can boost our resilience, calm the mind, and protect our long-term health.

Join me on today’s Cabral Concept 3415 as we explore the latest science on how to become more stress-resilient, naturally. Enjoy the episode and let me know what you think!

Show Highlights & Big Takeaways:

1. What Does the Research Show

A new study shows that enhancing CB1 receptor activity in the brain (especially in astrocytes) increases resilience to chronic stress. 

2. What Are CB1 Receptors

CB1 receptors are primarily located in the brain and central nervous system, though they’re also found in areas like the reproductive organs, liver, and some fat tissue. These receptors play a key role in regulating mood, memory, appetite, pain perception, and motor control. In other words, they influence many essential brain and nervous system functions—including how we move, how we feel, and how we respond to stress, anxiety, and depression.

3. What Are Ways to Enhance CB1 Receptors

Short-term use of full-spectrum CBD and small amounts of THC can help reduce stress and improve sleep over 6–12 weeks. For long-term support, natural strategies like daily exercise, omega-3s, quality sleep, intermittent fasting, and phytonutrients (such as turmeric, dark chocolate, and echinacea) help activate CB1 and CB2 receptors to regulate stress and mood.

Show Notes & Related Podcasts

Astrocytic cannabinoid receptor 1 promotes resilience by dampening stress-induced blood–brain barrier alterations (research)

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